US guide

Semaglutide in the US: FDA Status, Prices and Supplier Checks

Last reviewed 26 September 2026

Semaglutide is two different things in the US: an FDA-approved prescription drug sold as Ozempic, Wegovy and Rybelsus, and a research compound supplied to laboratories. This guide sets out which is which, what research-grade semaglutide costs, and how to check any supplier before ordering. To order research material, go to the semaglutide product page.

The short version

Two different products. Ozempic, Wegovy and Rybelsus are FDA-approved semaglutide, available only on prescription. Research-grade semaglutide is laboratory material and is not an FDA-approved drug.
Price. Eight strengths, 2 mg to 50 mg, in boxes of 10 vials from $5.50 (£4.18) per vial, every strength priced on the product page. Each box carries a batch-specific COA from Janoshik or Freedom Diagnostic.
Not for human use. If you are looking for a medicine, the lawful route in the US is a prescription from a licensed prescriber, filled by a licensed pharmacy. A research supplier is not that.

Semaglutide

8 strengths · boxes of 10 vials · batch COA

From $5.50 / vial (£4.18)

See prices

Laboratory research use only. Free delivery worldwide over $750.

Guide

What a US buyer should know

Points you can check independently. Nothing here is a claim about what semaglutide does, or a statement that it is safe or effective for any purpose.

An approved drug and a research compound

Semaglutide is a long-acting GLP-1 receptor agonist. Its phase 3 trials, including STEP 1 and SUSTAIN-6, are published in the New England Journal of Medicine,¹² and it is FDA-approved as Ozempic and Wegovy, and as Rybelsus, a tablet. All three are prescription-only. Research-grade semaglutide is the same molecule supplied as a lyophilized powder for laboratory work. It is not made, tested or released to FDA drug standards, so it is not Ozempic, Wegovy or Rybelsus and is never a substitute for any of them.

What happened to compounded semaglutide

During the national shortage, US compounding pharmacies were permitted to make semaglutide. The FDA declared the shortage resolved on February 21, 2025. Its grace period for state-licensed pharmacies ended on April 22, 2025, and for outsourcing facilities on May 22, 2025. That changed where US prescriptions are filled. It did not make research-grade material a drug.

What a Certificate of Analysis is worth

Every box ships with a batch-specific COA from Janoshik or Freedom Diagnostic. Batch-specific is the part that matters: a certificate for a different lot tells you nothing about the vial in your hand. Check the batch number on the certificate against the number printed on your box, and check that the laboratory named on it will confirm the report if asked.

What delivery to the US involves

We are a UK company. US orders ship FedEx tracked from our UK stock or direct from our verified manufacturer, depending on availability, and take 5–8 working days from dispatch. Any international parcel can be held, inspected or refused on entry to the US; if a US order is seized, we reship it once per customer at no cost, and a parcel whose tracking stalls is reshipped free. We hold no US stock.

References

1Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1). N Engl J Med (2021). PMID 33567185
2Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes (SUSTAIN-6). N Engl J Med (2016). PMID 27633186

Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.

Laboratory research use onlyNobelPepLab supplies semaglutide strictly for in vitro and laboratory research. We do not provide dosing guidance, do not make health claims, and do not supply products for human or veterinary use. Research-grade semaglutide is not Ozempic, Wegovy or Rybelsus and is not an FDA-approved drug.

Common questions

Is semaglutide FDA approved?

Yes, as Ozempic, Wegovy and Rybelsus, prescription-only drugs made by Novo Nordisk. Research-grade semaglutide is a different product and is not an FDA-approved drug.

Is research semaglutide the same as Ozempic or Wegovy?

It is the same molecule but not the same product. Ozempic and Wegovy are manufactured, tested and released under FDA approval. Research-grade semaglutide is a lyophilized powder in a sealed vial, made for laboratory use and verified by a batch Certificate of Analysis rather than by a drug regulator.

Is research semaglutide legal in the US?

It is laboratory material, not an FDA-approved drug, so there is no lawful route to supply it for human use, and a research-use-only label does not change that. It is supplied here as research material only. Our guide to US peptide law sets out the distinction in full.

How much does semaglutide cost in the US?

Research-grade semaglutide starts at $5.50 (£4.18) per vial in a box of ten, billed in US dollars, with all eight strengths priced per vial and per box on the product page. That is the price of laboratory material. It tells you nothing about the cost of a prescription.

Do you ship semaglutide to the US?

Yes, to all 50 states, FedEx tracked in 5–8 working days from dispatch. It ships from our UK stock or direct from our verified manufacturer; we have no US warehouse.

What strengths does semaglutide come in?

Eight: 2 mg, 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 mg and 50 mg, each in a box of ten vials.