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All products are for laboratory research purposes only. Not for human consumption.

Synthetic dual incretin receptor agonist peptide

Tirzepatide

Tirzepatide is a synthetic 39-residue peptide that acts as a dual agonist at the GIP and GLP-1 receptors. The backbone carries a C20 diacid fatty-acid conjugate that extends its plasma half-life through albumin binding. It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.

From $8.00 per vial · £6.32

$80.00 (£63.20) per box of 10 vials · 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 100 mg, 120 mg

Vial of Tirzepatide research peptide, supplied in boxes of 10

Overview

What is Tirzepatide?

Tirzepatide is a synthetic 39-residue peptide that acts as a dual agonist at the GIP and GLP-1 receptors. The backbone carries a C20 diacid fatty-acid conjugate that extends its plasma half-life through albumin binding. It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.

Laboratory research use onlyNobelPepLab supplies Tirzepatide strictly for in vitro and laboratory research. We do not provide dosing guidance, do not make health claims, and do not supply products for human or veterinary use.

Tirzepatide at a glance

CompoundTirzepatide
Also known asLY3298176, dual agonist peptide, tirzepatide acetate
ClassificationSynthetic dual incretin receptor agonist peptide
CAS number2023788-19-2
Molecular formulaC225H348N48O68
Molecular weight4813.45 g/mol
Sequence39-residue backbone with a C20 diacid fatty-acid conjugate
Purity99%+ by HPLC
Physical formLyophilised powder
Available strengths10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 100 mg, 120 mg
Box quantity10 vials
Price from$8.00 per vial ($80.00 per box)
Research statusAn approved prescription medicine in the UK and elsewhere. Supply outside the regulated pharmaceutical chain is unlawful. Included here strictly as a laboratory reference material.
DocumentationBatch-specific COA (Janoshik or Freedom Diagnostic)

Nominal specifications. The authoritative figures for any given box are those printed on its batch COA.

Pricing

How much does Tirzepatide cost?

Tirzepatide starts at $8.00 per vial (£6.32), sold in boxes of 10 at $80.00. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.

Tirzepatide price by strength. Billed in USD; GBP shown as an indicative conversion. Each box contains 10 vials.
StrengthPer vialBox of 10
10 mg$8.00 £6.32$80.00 £63.20
15 mg$9.09 £7.18$90.85 £71.77
20 mg$9.83 £7.77$98.28 £77.64
30 mg$11.69 £9.24$116.85 £92.31
40 mg$13.17 £10.40$131.71 £104.05
50 mg$15.40 £12.17$154.00 £121.66
60 mg$16.33 £12.90$163.28 £128.99
100 mg$23.39 £18.48$233.85 £184.74
120 mg$25.43 £20.09$254.28 £200.88
Important: Tirzepatide is a licensed medicine in the UK and many other jurisdictions. It is supplied here strictly as a reference material for laboratory research. Buyers are responsible for confirming that possession and use are lawful in their own jurisdiction.

Handling

How should Tirzepatide be stored and reconstituted?

Lyophilised storage. Sealed vials are stable at room temperature for short periods during transit. For longer-term storage keep at −20 °C, protected from light and moisture.
Reconstitution. Bacteriostatic or sterile water is introduced slowly down the inside wall of the vial. Do not inject the stream directly into the powder and do not shake.
Dissolving. Swirl gently until clear. Peptides are shear-sensitive; vigorous agitation can degrade the compound.
After reconstitution. Refrigerate at 2–8 °C. Reconstituted peptide has a materially shorter working life than the lyophilised form.
Freeze–thaw. Repeated cycles degrade peptides. Aliquot before freezing where a protocol requires multiple uses.

Research Context

What is Tirzepatide researched for?

Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what Tirzepatide does, and nothing here is a statement that it is safe or effective for any purpose.

Research status An approved prescription medicine in the UK and elsewhere. Supply outside the regulated pharmaceutical chain is unlawful. Included here strictly as a laboratory reference material.

Dual receptor activation

Tirzepatide activates both the GIP and GLP-1 receptors from one molecule. It is not a balanced agonist: it is considerably more potent at GIP, and how that imbalance contributes to the overall effect is still an open research question. 1

The role of GIP

GIP is the interesting part. On its own it does little for body weight, yet combined with GLP-1 activation the effect appears larger than GLP-1 alone. Working out why is an active area of incretin research.

Comparative incretin studies

Sitting between semaglutide (single agonist) and retatrutide (triple agonist), tirzepatide is a standard midpoint in receptor selectivity and potency comparisons. 12

References

  1. 1Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1). N Engl J Med (2022). PMID 35658024
  2. 2Tirzepatide for Obesity Treatment and Diabetes Prevention. N Engl J Med (2025). PMID 39536238

Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.

Read this before citing any of the abovePreclinical means the work was done in cells or animals. Results in those systems very often fail to reproduce in humans. NobelPepLab supplies Tirzepatide for laboratory research only, does not provide dosing guidance, and does not supply products for human or veterinary use.

Applications

Where Tirzepatide is used in the laboratory

  • Dual incretin receptor pharmacology and comparative binding studies
  • Receptor selectivity profiling against single-agonist reference compounds
  • Fatty-acylated peptide stability and formulation research
  • Analytical characterisation of long-acting incretin analogues

Verification

Does Tirzepatide come with a COA?

Yes — every box. Each batch of Tirzepatide is analysed by Janoshik Analytical or Freedom Diagnostic. The certificate confirms identity by mass spectrometry and purity by HPLC, and is tied to the batch number printed on the vial label. You can ask to see it before you order.

HPLC chromatogram with the quantified purity figure
Mass spectrometry confirming molecular weight against the theoretical value
Batch or lot reference matching the vial label
Laboratory letterhead, test date and analyst signature
Example Certificate of Analysis issued by Janoshik Analytical

Example COA. You receive the certificate matching your own batch.

Questions

Tirzepatide questions, answered

How does tirzepatide differ from retatrutide?

Both are long-acting incretin agonists built on a similar acylated peptide scaffold. Tirzepatide is a dual agonist, binding the GIP and GLP-1 receptors. Retatrutide is a triple agonist, adding activity at the glucagon receptor. In receptor-selectivity work the two are frequently run side by side for exactly that reason.

How much does Tirzepatide cost?

Tirzepatide starts at $8.00 per vial, sold in boxes of 10 vials at $80.00 per box (about £63.20). 9 strengths available: 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 100 mg, 120 mg. There is no minimum order.

What purity is your Tirzepatide?

All batches test at 99%+ purity. Every box ships with a batch-specific Certificate of Analysis from Janoshik Analytical or Freedom Diagnostic, confirming identity by mass spectrometry and purity by HPLC.

Is there a minimum order for Tirzepatide?

No. You can order a single box of 10 vials. There is no trade account, bulk commitment or minimum spend.

How is Tirzepatide shipped?

Tracked and in discreet, plain packaging, dispatched within 1–3 working days. Delivery estimates are UK 5–7 working days, EU 8–10, USA 5–8 and rest of world 10–12. Full detail is on the shipping page.