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Repair, Recovery & Immune In stock · dispatched in 1–2 working days

TB-500 Peptide Vials

Synthetic fragment of Thymosin Beta-4 · 5mg–10mg · boxes of 10 vials

$93.00 £69.68 per box of 10 vials
$9.30 per vial · £6.97
$136.92 £102.58 per box of 10 vials
$13.69 per vial · £10.26

Free delivery worldwide on orders over $1,000 (about £749)

Strength 2 options · price per box

Lab report for this strengthSent free on WhatsApp on request

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Boxes

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  • No minimumBoxes of 10 vials
  • Tracked shippingDispatched in 1–2 working days
  • Batch COAFree on request
  • Photographed firstBefore it ships

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Often ordered together

TB-500 5 mg$93.00 / box
Bacteriostatic Water 3 mL$9.00 / box
2 boxes, 20 vials$102.00

One box of each. Change strengths or quantities in the cart.

Also ordered with TB-500

About TB-500

What is TB-500?

Overview

What is TB-500?

TB-500 is a synthetic acetylated seven-residue fragment (Ac-LKKTETQ) corresponding to the actin-binding domain of Thymosin Beta-4. It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.

Laboratory research use onlyNobelPepLab supplies TB-500 strictly for in vitro and laboratory research. We do not provide dosing guidance, do not make health claims, and do not supply products for human or veterinary use.

TB-500 at a glance

TB-500 specifications
CompoundTB-500
Also known asTB500, Thymosin Beta-4 fragment, Ac-LKKTETQ, Thymosin B4, TB-500 peptide
ClassificationSynthetic fragment of Thymosin Beta-4
CAS number885340-08-9
Molecular formulaC38H68N10O14
Molecular weight889.0 g/mol
SequenceAc-LKKTETQ (acetylated 7-residue active fragment)
PubChem CID62707662
Purity99%+ by HPLC
Physical formLyophilised powder
Available strengths5 mg, 10 mg
Box quantity10 vials
Price from$9.30 per vial ($93.00 per box)
Research statusPreclinical. Full-length Thymosin Beta-4 has been through early clinical trials; the fragment has not. Prohibited in competitive sport under the WADA S2 category.
DocumentationBatch-specific third-party COA

These are catalogue target specifications, not batch results. The 99%+ purity figure is the specification we buy to. The authoritative figures for any particular box are the ones printed on that box’s Certificate of Analysis, which is lot-specific. What research grade actually means explains the difference. Terms such as HPLC purity and net peptide content are explained in the peptide glossary.

We make no “third-party verified” claim for a batch unless the matching report is supplied with it. Ask for the current COA for the lot in stock before you order — we will send it.

Prices for every strength

Pricing

TB-500 price per vial: 5mg and 10mg

TB-500 starts at $9.30 per vial (£6.97), sold in boxes of 10 at $93.00. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.

TB-500 price by strength. Billed in USD; GBP shown for reference. Each box contains 10 vials.
StrengthPer vialBox of 10
5 mg$9.30 £6.97$93.00 £69.68
10 mg$13.69 £10.26$136.92 £102.58
Important: Suppliers differ in what they label TB-500. Confirm the molecular weight on your batch COA to establish whether you have received the seven-residue fragment or full-length Thymosin Beta-4.
Storage & reconstitution

Handling

How should TB-500 be stored and reconstituted?

Sealed vials tolerate ambient temperature in transit and keep at −20 °C beyond that. Reconstitute slowly down the vial wall, swirl rather than shake, then refrigerate at 2–8 °C and aliquot before freezing.

What it is researched for

Research Context

What is TB-500 researched for?

Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what TB-500 does, and nothing here is a statement that it is safe or effective for any purpose.

Research status Preclinical. Full-length Thymosin Beta-4 has been through early clinical trials; the fragment has not. Prohibited in competitive sport under the WADA S2 category.

Actin binding and cell movement

The LKKTETQ sequence is the region of Thymosin Beta-4 that binds actin, the filament protein that gives cells their shape and allows them to move. By holding actin monomers in reserve it changes how quickly cells can reorganise and migrate. 1

Wound and tissue repair models

Cell migration is the first step in closing a wound, which is why most research uses scratch assays and animal wound models. Full-length Thymosin Beta-4 reached early clinical trials for corneal and skin wounds. 12

Cardiac and vascular research

Thymosin Beta-4 has been studied in models of heart injury, where it appears to influence the behaviour of cells in the outer layer of the heart. 2

References

  1. 1Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues. Trends Mol Med (2005). PMID 16099219
  2. 2The actin binding site on thymosin beta4 promotes angiogenesis. FASEB J (2003). PMID 14500546

Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.

Read this before citing any of the abovePreclinical means the work was done in cells or animals. Results in those systems very often fail to reproduce in humans. NobelPepLab supplies TB-500 for laboratory research only, does not provide dosing guidance, and does not supply products for human or veterinary use.
Laboratory uses

Applications

Where TB-500 is used in the laboratory

  • Actin sequestration and cytoskeletal dynamics studies
  • Cell migration and in vitro wound-model research
  • Comparative studies against full-length Thymosin Beta-4
  • Peptide fragment structure-activity research
Batch COA

Verification

Does TB-500 come with a COA?

Yes — every box. Each batch of TB-500 is analysed by an independent third-party laboratory, and the certificate is tied to the batch number on the vial label.

Example Certificate of Analysis, not the certificate for this batch

Example COA. You receive the certificate matching your own batch.

Questions & answers

Questions

TB-500 questions, answered

Is TB-500 the same as Thymosin Beta-4?

Not necessarily, and this is worth checking carefully. TB-500 most commonly refers to the acetylated seven-residue fragment Ac-LKKTETQ (around 889 g/mol), whereas full-length Thymosin Beta-4 is a 43-residue peptide of around 4963 g/mol. Different suppliers use the name for different molecules. Always confirm which form you have received against the molecular weight stated on the batch COA.

How much does TB-500 cost?

TB-500 starts at $9.30 per vial, sold in boxes of 10 vials at $93.00 per box (about £69.68). 2 strengths available: 5 mg, 10 mg. There is no minimum order.

Can I buy TB-500 10mg vials in the UK?

Yes. TB-500 10mg comes in boxes of 10 vials at $136.92 per box ($13.69 per vial, about £102.58 per box), sent tracked to UK addresses. There is no minimum order.

Do you ship TB-500 to the US?

Yes, to all 50 states. TB-500 ships FedEx tracked from our UK stock or direct from our verified manufacturer, arriving 5 to 8 working days after dispatch, and is billed in US dollars from $9.30 per vial. We hold no US stock. If US customs seize an order, we reship it once at no cost. Our guide for US buyers covers US shipping, customs and pricing in full.

How is TB-500 shipped to the UK and USA?

Tracked to the UK, USA, EU and worldwide, in plain packaging, dispatched within 1–2 working days. Country-by-country estimates are on the shipping page.