KPV Peptide Vials
C-terminal tripeptide of alpha-MSH (3 residues) · 10mg–50mg · boxes of 10 vials
Free delivery worldwide on orders over $1,000 (about £749)
Strength 3 options · price per box
Latest third-party test: 99.79%Purity (HPLC) · 10 mg · tested 9 Jul 2026
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- No minimumBoxes of 10 vials
- Tracked shippingDispatched in 1–2 working days
- Batch COAFree on request
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Often ordered together
One box of each. Change strengths or quantities in the cart.
Also ordered with KPV
About KPV
What is KPV?
Overview
What is KPV?
KPV is a tripeptide of lysine, proline and valine - the last three residues of alpha-melanocyte-stimulating hormone (alpha-MSH). Published work reports that this short fragment retains much of the parent hormone's anti-inflammatory activity in cell and animal models without the melanocortin receptor binding that drives pigmentation. Supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
KPV at a glance
| Compound | KPV |
|---|---|
| Also known as | Lysine-Proline-Valine, alpha-MSH (11-13), KPV tripeptide, H-Lys-Pro-Val-OH, KPV peptide |
| Classification | C-terminal tripeptide of alpha-MSH (3 residues) |
| CAS number | 67727-97-3 |
| Molecular formula | C16H30N4O4 |
| Molecular weight | 342.44 g/mol |
| Sequence | Lys-Pro-Val |
| PubChem CID | 125672 |
| Purity | 99%+ by HPLC |
| Physical form | Lyophilised powder |
| Available strengths | 10 mg, 30 mg, 50 mg |
| Box quantity | 10 vials |
| Price from | $8.09 per vial ($80.85 per box) |
| Research status | Preclinical. Studied in cell culture and in rodent models, most often chemically induced colitis. No approved human use and no completed large clinical trials. |
| Documentation | Batch-specific third-party COA |
These are catalogue target specifications, not batch results. The 99%+ purity figure is the specification we buy to. The authoritative figures for any particular box are the ones printed on that box’s Certificate of Analysis, which is lot-specific. What research grade actually means explains the difference. Terms such as HPLC purity and net peptide content are explained in the peptide glossary.
We make no “third-party verified” claim for a batch unless the matching report is supplied with it. Ask for the current COA for the lot in stock before you order — we will send it.
Prices for every strength
Pricing
KPV price per vial: 10mg, 30mg and 50mg
KPV starts at $8.09 per vial (£6.06), sold in boxes of 10 at $80.85. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.
| Strength | Per vial | Box of 10 |
|---|---|---|
| 10 mg | $8.09 £6.06 | $80.85 £60.57 |
| 30 mg | $14.05 £10.53 | $140.52 £105.28 |
| 50 mg | $17.84 £13.37 | $178.35 £133.62 |
Storage & reconstitution
Handling
How should KPV be stored and reconstituted?
Sealed vials tolerate ambient temperature in transit and keep at −20 °C beyond that. Reconstitute slowly down the vial wall, swirl rather than shake, then refrigerate at 2–8 °C and aliquot before freezing.
Why each of those matters, and what a freeze–thaw cycle actually costs: peptide handling and storage reference. How long a mixed vial keeps: reconstituted peptide shelf life.
What it is researched for
Research Context
What is KPV researched for?
Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what KPV does, and nothing here is a statement that it is safe or effective for any purpose.
Switching off inflammatory signalling
KPV is reported to enter cells and reduce the activity of NF-kB, the switch that turns on inflammatory genes. In cultured immune and gut lining cells this lowers the output of signalling molecules such as IL-6 and IL-8. Almost all of the KPV literature is built around this mechanism. 1
Gut inflammation models
The most-cited KPV work uses mice with chemically induced colitis. Reported findings include less weight loss, lower tissue damage scores and reduced inflammatory markers in the colon. These are rodent results; no equivalent human trial has been completed. 1
How a three-residue peptide gets into cells
KPV appears to be carried intact into intestinal and immune cells by PepT1, a transporter that normally handles small peptides left over from digested food. That delivery route is unusual and is part of why researchers study the short fragment rather than the whole hormone. 1
Antimicrobial activity in culture
Separate studies report that KPV inhibits the growth of Candida albicans and Staphylococcus aureus in culture. This is an in vitro finding at defined concentrations and has not been developed into any approved treatment.
References
- 1PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology (2008). PMID 18061177
Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.
Laboratory uses
Applications
Where KPV is used in the laboratory
- Innate immune signalling research, particularly NF-kB pathway activity in cultured immune and epithelial cells
- Gastrointestinal inflammation models, including chemically induced colitis in rodents
- PepT1 peptide transporter studies, since KPV is reported to be taken up intact by intestinal and immune cells
- Comparative work alongside full-length alpha-MSH and other melanocortin fragments
- Antimicrobial screening against Candida albicans and Staphylococcus aureus in culture
Batch COA
Verification
Does KPV come with a COA?
Yes — every box. Each batch of KPV is analysed by an independent third-party laboratory, and the certificate is tied to the batch number on the vial label.
Example COA. You receive the certificate matching your own batch.
Questions & answers
Questions
KPV questions, answered
What is KPV peptide?
KPV is a tripeptide — three amino acids, lysine, proline and valine — corresponding to the last three residues of alpha-melanocyte-stimulating hormone. At three residues it is one of the shortest compounds in this catalogue, and it is supplied as a lyophilised powder for laboratory research use only.
How is KPV different from alpha-MSH?
KPV is the final three amino acids of alpha-MSH, a 13-residue hormone. Studies report that this fragment keeps the anti-inflammatory activity of the whole hormone in cell and animal models while lacking the receptor binding that produces skin pigmentation. Separating those two effects is the main reason KPV is studied on its own rather than as part of the parent sequence.
How much does KPV cost?
KPV starts at $8.09 per vial, sold in boxes of 10 vials at $80.85 per box (about £60.57). 3 strengths available: 10 mg, 30 mg, 50 mg. There is no minimum order.
Can I buy KPV 10mg vials in the UK?
Yes. KPV 10mg comes in boxes of 10 vials at $80.85 per box ($8.09 per vial, about £60.57 per box), sent tracked to UK addresses. There is no minimum order.
How is KPV shipped to the UK and USA?
Tracked to the UK, USA, EU and worldwide, in plain packaging, dispatched within 1–2 working days. Country-by-country estimates are on the shipping page.
