All products are for laboratory research purposes only. Not for human consumption.
Modified C-terminal fragment of human growth hormone
AOD-9604
AOD-9604 is a modified fragment of human growth hormone corresponding to residues 177 to 191, with an additional tyrosine at the N-terminus to aid stability and analysis. It carries none of the full hormone's receptor-binding regions. It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
$110.57 (£87.35) per box of 10 vials · 5 mg, 10 mg
Overview
What is AOD-9604?
AOD-9604 is a modified fragment of human growth hormone corresponding to residues 177 to 191, with an additional tyrosine at the N-terminus to aid stability and analysis. It carries none of the full hormone's receptor-binding regions. It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
AOD-9604 at a glance
| Compound | AOD-9604 |
|---|---|
| Also known as | AOD9604, Anti-Obesity Drug 9604, AOD 9604 |
| Classification | Modified C-terminal fragment of human growth hormone |
| CAS number | 221231-10-3 |
| Molecular formula | C78H123N23O23S2 |
| Molecular weight | 1815.1 g/mol |
| Sequence | Tyr-hGH(177-191) |
| Purity | 99%+ by HPLC |
| Physical form | Lyophilised powder |
| Available strengths | 5 mg, 10 mg |
| Box quantity | 10 vials |
| Price from | $11.06 per vial ($110.57 per box) |
| Research status | Not approved as a medicine. Reached Phase 2 clinical trials for obesity and did not meet its endpoints. Has been assessed as safe by the US FDA as a food ingredient. |
| Documentation | Batch-specific COA (Janoshik or Freedom Diagnostic) |
Nominal specifications. The authoritative figures for any given box are those printed on its batch COA.
Pricing
How much does AOD-9604 cost?
AOD-9604 starts at $11.06 per vial (£8.74), sold in boxes of 10 at $110.57. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.
| Strength | Per vial | Box of 10 |
|---|---|---|
| 5 mg | $11.06 £8.74 | $110.57 £87.35 |
| 10 mg | $16.03 £12.66 | $160.28 £126.62 |
Handling
How should AOD-9604 be stored and reconstituted?
Full explanation of why each of these matters: peptide handling and storage reference.
Research Context
What is AOD-9604 researched for?
Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what AOD-9604 does, and nothing here is a statement that it is safe or effective for any purpose.
Separating fat metabolism from growth
The C-terminal region of growth hormone appears to carry its fat-metabolising activity separately from its growth-promoting activity. AOD-9604 was built specifically to test that separation in adipocyte culture and animal models. 12
No growth or IGF-1 effect
Because it lacks the receptor-binding regions of the full hormone, AOD-9604 does not raise IGF-1 or produce growth effects. That is the entire design rationale and the main thing distinguishing it from growth hormone itself. 1
Clinical outcome
A Phase 2 obesity trial did not show a significant weight difference against placebo. That negative result is an important and often omitted part of the compound's record.
References
- 1Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment. Int J Obes Relat Metab Disord (2001). PMID 11673763
- 2Reduction of cumulative body weight gain and adipose tissue mass in obese mice: response to chronic treatment with synthetic hGH 177-191 peptide. Biochem Mol Biol Int (1994). PMID 7987248
Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.
Applications
Where AOD-9604 is used in the laboratory
- Growth hormone fragment structure-activity research
- Lipid metabolism studies in adipocyte culture
- Comparative work against the unmodified hGH 176-191 fragment
- Analytical characterisation of modified peptide fragments
Verification
Does AOD-9604 come with a COA?
Yes — every box. Each batch of AOD-9604 is analysed by Janoshik Analytical or Freedom Diagnostic. The certificate confirms identity by mass spectrometry and purity by HPLC, and is tied to the batch number printed on the vial label. You can ask to see it before you order.
Example COA. You receive the certificate matching your own batch.
Questions
AOD-9604 questions, answered
How does AOD-9604 differ from HGH Fragment 176-191?
They are closely related. HGH Fragment 176-191 is the unmodified C-terminal fragment of human growth hormone. AOD-9604 is that region with a tyrosine residue added at the N-terminus, which improves stability and gives a distinct molecular weight. Both are stocked separately so they can be compared directly.
How much does AOD-9604 cost?
AOD-9604 starts at $11.06 per vial, sold in boxes of 10 vials at $110.57 per box (about £87.35). 2 strengths available: 5 mg, 10 mg. There is no minimum order.
What purity is your AOD-9604?
All batches test at 99%+ purity. Every box ships with a batch-specific Certificate of Analysis from Janoshik Analytical or Freedom Diagnostic, confirming identity by mass spectrometry and purity by HPLC.
Is there a minimum order for AOD-9604?
No. You can order a single box of 10 vials. There is no trade account, bulk commitment or minimum spend.
How is AOD-9604 shipped?
Tracked and in discreet, plain packaging, dispatched within 1–3 working days. Delivery estimates are UK 5–7 working days, EU 8–10, USA 5–8 and rest of world 10–12. Full detail is on the shipping page.
Catalog
