PT-141 Peptide Vials
Cyclic lactam heptapeptide melanocortin receptor agonist · 10mg · boxes of 10 vials
Free delivery worldwide on orders over $1,000 (about £749)
Strength 1 option · price per box
Latest third-party test: 99.81%Purity (HPLC) · 10 mg · tested 23 Oct 2026
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Often ordered together
One box of each. Change strengths or quantities in the cart.
About PT-141
What is PT-141?
Overview
What is PT-141?
PT-141 is a cyclic lactam heptapeptide and a metabolite of Melanotan II, differing from it by a free carboxylic acid at the C-terminus in place of the amide. That single change shifts its receptor selectivity profile. It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
PT-141 at a glance
| Compound | PT-141 |
|---|---|
| Also known as | Bremelanotide, PT141, PT 141 |
| Classification | Cyclic lactam heptapeptide melanocortin receptor agonist |
| CAS number | 189691-06-3 |
| Molecular formula | C50H68N14O10 |
| Molecular weight | 1025.16 g/mol |
| Sequence | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH |
| PubChem CID | 9941379 |
| Purity | 99%+ by HPLC |
| Physical form | Lyophilised powder |
| Available strengths | 10 mg |
| Box quantity | 10 vials |
| Price from | $8.59 per vial ($85.85 per box) |
| Research status | Approved in the US as bremelanotide for one specific indication. Not approved in the UK. Research-grade material is not the approved pharmaceutical product. |
| Documentation | Batch-specific third-party COA |
These are catalogue target specifications, not batch results. The 99%+ purity figure is the specification we buy to. The authoritative figures for any particular box are the ones printed on that box’s Certificate of Analysis, which is lot-specific. What research grade actually means explains the difference. Terms such as HPLC purity and net peptide content are explained in the peptide glossary.
We make no “third-party verified” claim for a batch unless the matching report is supplied with it. Ask for the current COA for the lot in stock before you order — we will send it.
Prices for every strength
Pricing
PT-141 price per vial: 10mg
PT-141 starts at $8.59 per vial (£6.44), sold in boxes of 10 at $85.85. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.
| Strength | Per vial | Box of 10 |
|---|---|---|
| 10 mg | $8.59 £6.44 | $85.85 £64.32 |
Storage & reconstitution
Handling
How should PT-141 be stored and reconstituted?
Sealed vials tolerate ambient temperature in transit and keep at −20 °C beyond that. Reconstitute slowly down the vial wall, swirl rather than shake, then refrigerate at 2–8 °C and aliquot before freezing.
Why each of those matters, and what a freeze–thaw cycle actually costs: peptide handling and storage reference. How long a mixed vial keeps: reconstituted peptide shelf life.
What it is researched for
Research Context
What is PT-141 researched for?
Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what PT-141 does, and nothing here is a statement that it is safe or effective for any purpose.
Central rather than vascular action
Unlike compounds that act on blood flow, PT-141 works through melanocortin receptors in the central nervous system. That difference in mechanism is the reason it was developed and the focus of most of the research. 12
MC3R and MC4R selectivity
Changing the C-terminal amide of Melanotan II to a free acid reduces activity at MC1R, the pigmentation receptor, and shifts the profile toward MC3R and MC4R. It is a textbook demonstration of how one terminal change redirects receptor selectivity.
Melanocortin receptor mapping
Used alongside Melanotan II in binding assays to determine which receptor subtype is responsible for which observed effect, since the two differ at a single position.
References
- 1Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials (RECONNECT). Obstet Gynecol (2019). PMID 31599840
- 2Long-Term Safety and Efficacy of Bremelanotide for Hypoactive Sexual Desire Disorder. Obstet Gynecol (2019). PMID 31599847
Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.
Laboratory uses
Applications
Where PT-141 is used in the laboratory
- Melanocortin receptor subtype selectivity studies, particularly MC3R and MC4R
- Comparative binding research against Melanotan II
- Cyclic peptide conformational stability studies
- Structure-activity relationship research on alpha-MSH analogues
Batch COA
Verification
Does PT-141 come with a COA?
Yes — every box. Each batch of PT-141 is analysed by an independent third-party laboratory, and the certificate is tied to the batch number on the vial label.
Example COA. You receive the certificate matching your own batch.
Questions & answers
Questions
PT-141 questions, answered
How is PT-141 related to Melanotan II?
PT-141 is a metabolite of Melanotan II. The two share an identical cyclic core; PT-141 terminates in a free carboxylic acid where Melanotan II carries an amide. That difference reduces activity at MC1R, the receptor most associated with pigmentation, which is why the two show measurably different selectivity profiles.
How much does PT-141 cost?
PT-141 starts at $8.59 per vial, sold in boxes of 10 vials at $85.85 per box (about £64.32). 1 strength available: 10 mg. There is no minimum order.
Can I buy PT-141 10mg vials in the UK?
Yes. PT-141 10mg comes in boxes of 10 vials at $85.85 per box ($8.59 per vial, about £64.32 per box), sent tracked to UK addresses. There is no minimum order.
How is PT-141 shipped to the UK and USA?
Tracked to the UK, USA, EU and worldwide, in plain packaging, dispatched within 1–2 working days. Country-by-country estimates are on the shipping page.
