Matrixyl Peptide Vials
Palmitoyl pentapeptide-4 (Pal-KTTKS) powder · 10mg · for sale in the UK & US, boxes of 10 vials
Free delivery worldwide on orders over $1,000 (about £749)
Strength 1 option · price per box
Boxes
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- No minimumBoxes of 10 vials
- Tracked shippingDispatched in 1–2 working days
- Batch COAFree on request
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Often ordered together
One box of each. Change strengths or quantities in the cart.
About Matrixyl
What is Matrixyl?
Overview
What is Matrixyl?
Matrixyl peptide powder is for sale in the UK and US in boxes of 10 vials of 10 mg, supplied as research material rather than a skincare product. Matrixyl is palmitoyl pentapeptide-4: a five-residue fragment of type I collagen - lysine, threonine, threonine, lysine, serine - with a sixteen-carbon palmitic acid chain attached. The peptide itself is a piece of the propeptide released when collagen is broken down, and the working hypothesis is that its presence signals to fibroblasts that matrix repair is needed. Supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
Matrixyl at a glance
| Compound | Matrixyl |
|---|---|
| Also known as | Palmitoyl pentapeptide-4, Pal-KTTKS, Palmitoyl oligopeptide, Matrixyl peptide |
| Classification | Palmitoylated collagen-fragment pentapeptide used in dermal matrix research |
| CAS number | 214047-00-4 |
| Molecular formula | C39H75N7O10 |
| Molecular weight | 802.1 g/mol |
| Sequence | Pal-Lys-Thr-Thr-Lys-Ser (Pal-KTTKS) |
| PubChem CID | 9897237 |
| Purity | 99%+ by HPLC |
| Physical form | Lyophilised powder |
| Available strengths | 10 mg |
| Box quantity | 10 vials |
| Price from | $7.29 per vial ($72.85 per box) |
| Research status | The pentapeptide KTTKS is a fragment of the type I collagen propeptide, and the research question is whether presenting that fragment to fibroblasts prompts them to lay down more matrix. Cell-culture work and small clinical studies exist. The literature is considerably thinner than the marketing around it, and most published work uses the palmitoylated form at cosmetic concentrations. |
| Documentation | Batch-specific third-party COA |
These are catalogue target specifications, not batch results. The 99%+ purity figure is the specification we buy to. The authoritative figures for any particular box are the ones printed on that box’s Certificate of Analysis, which is lot-specific. What research grade actually means explains the difference. Terms such as HPLC purity and net peptide content are explained in the peptide glossary.
We make no “third-party verified” claim for a batch unless the matching report is supplied with it. Ask for the current COA for the lot in stock before you order — we will send it.
Prices for every strength
Pricing
Matrixyl price per vial: 10mg
Matrixyl starts at $7.29 per vial (£5.46), sold in boxes of 10 at $72.85. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.
| Strength | Per vial | Box of 10 |
|---|---|---|
| 10 mg | $7.29 £5.46 | $72.85 £54.58 |
Storage & reconstitution
Handling
How should Matrixyl be stored and reconstituted?
Sealed vials tolerate ambient temperature in transit and keep at −20 °C beyond that. Reconstitute slowly down the vial wall, swirl rather than shake, then refrigerate at 2–8 °C and aliquot before freezing.
Why each of those matters, and what a freeze–thaw cycle actually costs: peptide handling and storage reference. How long a mixed vial keeps: reconstituted peptide shelf life.
What it is researched for
Research Context
What is Matrixyl researched for?
Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what Matrixyl does, and nothing here is a statement that it is safe or effective for any purpose.
The collagen fragment hypothesis
KTTKS is released when type I collagen is broken down. The reasoning behind using it as an active is that a fragment of degraded collagen may act as a feedback signal that repair is needed. In tendon-cell culture the pentapeptide increased expression of type I collagen and transforming growth factor beta, which is the most direct published support for the idea. 1
Wound and matrix work
The palmitoylated form has been examined in wound-contraction models alongside connective tissue growth factor, which extends the question from collagen expression alone to the broader matrix response. 2
What is not established
Most published work is cell culture or small studies. Whether effects at those concentrations translate to intact human skin at the concentrations used in formulation is unsettled, and independent replication is limited.
References
- 1The pentapeptide KTTKS promoting the expressions of type I collagen and transforming growth factor-beta of tendon cells. J Orthop Res (2007). PMID 17593541
- 2Effect of Palmitoyl-Pentapeptide (Pal-KTTKS) on Wound Contractile Process in Relation with Connective Tissue Growth Factor. Tissue Eng Regen Med (2017). PMID 30603464
Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.
Laboratory uses
Applications
Where Matrixyl is used in the laboratory
- Dermal matrix research, where the KTTKS fragment is studied for its effect on type I collagen expression in fibroblast culture
- Comparative work alongside GHK-Cu, the other widely researched matrix-signalling peptide in this catalogue
- Delivery and permeation studies, since the palmitoyl chain exists specifically to address the difficulty of moving a hydrophilic pentapeptide across a lipid barrier
- Wound and connective-tissue models, where the palmitoylated form has been examined alongside connective tissue growth factor
Batch COA
Verification
Does Matrixyl come with a COA?
Yes — every box. Each batch of Matrixyl is analysed by an independent third-party laboratory, and the certificate is tied to the batch number on the vial label.
Example COA. You receive the certificate matching your own batch.
Questions & answers
Questions
Matrixyl questions, answered
Why is it palmitoylated?
Because KTTKS on its own is hydrophilic and crosses lipid membranes poorly. Attaching a fatty acid makes the molecule amphiphilic and improves partitioning into the stratum corneum in permeation studies. The palmitoyl chain is a delivery decision rather than the active part - the signalling fragment is the pentapeptide.
Is Matrixyl the same as Matrixyl 3000?
No. Matrixyl is palmitoyl pentapeptide-4 (Pal-KTTKS), a single peptide. Matrixyl 3000 is a different cosmetic ingredient made of two other peptides, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7. We supply the original single peptide.
How is Matrixyl different from Argireline?
They are studied for different things. Matrixyl is a collagen fragment studied as a signal to fibroblasts to rebuild matrix. Argireline is a fragment of the SNAP-25 protein studied for its effect on neurotransmitter release; our SNAP-8 is its longer relative.
Can I buy Matrixyl peptide powder in the UK?
Yes. 10 mg vials of lyophilised powder in boxes of 10, dispatched in 1–2 working days with tracked UK delivery at a fixed price shown in your cart, free on orders over $1,000. Batch COA free on request. It is research material, not a cosmetic product.
How much does Matrixyl cost?
Matrixyl starts at $7.29 per vial, sold in boxes of 10 vials at $72.85 per box (about £54.58). 1 strength available: 10 mg. There is no minimum order.
Can I buy Matrixyl 10mg vials in the UK?
Yes. Matrixyl 10mg comes in boxes of 10 vials at $72.85 per box ($7.29 per vial, about £54.58 per box), sent tracked to UK addresses. There is no minimum order.
How is Matrixyl shipped to the UK and USA?
Tracked to the UK, USA, EU and worldwide, in plain packaging, dispatched within 1–2 working days. Country-by-country estimates are on the shipping page.
