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Synthetic nonapeptide
DSIP
DSIP, or delta sleep-inducing peptide, is a synthetic nonapeptide first identified in studies of cerebral venous blood during slow-wave sleep. It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
$77.85 (£61.50) per box of 10 vials · 5 mg, 10 mg, 15 mg
Overview
What is DSIP?
DSIP, or delta sleep-inducing peptide, is a synthetic nonapeptide first identified in studies of cerebral venous blood during slow-wave sleep. It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
DSIP at a glance
| Compound | DSIP |
|---|---|
| Also known as | Delta sleep-inducing peptide, DSIP acetate |
| Classification | Synthetic nonapeptide |
| CAS number | 62568-57-4 |
| Molecular formula | C35H48N10O15 |
| Molecular weight | 848.81 g/mol |
| Sequence | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu |
| Purity | 99%+ by HPLC |
| Physical form | Lyophilised powder |
| Available strengths | 5 mg, 10 mg, 15 mg |
| Box quantity | 10 vials |
| Price from | $7.79 per vial ($77.85 per box) |
| Research status | Not approved anywhere. Research is sparse and much of it dates from the 1970s and 1980s. Its role in the body remains unconfirmed. |
| Documentation | Batch-specific COA (Janoshik or Freedom Diagnostic) |
Nominal specifications. The authoritative figures for any given box are those printed on its batch COA.
Pricing
How much does DSIP cost?
DSIP starts at $7.79 per vial (£6.15), sold in boxes of 10 at $77.85. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.
| Strength | Per vial | Box of 10 |
|---|---|---|
| 5 mg | $7.79 £6.15 | $77.85 £61.50 |
| 10 mg | $9.64 £7.62 | $96.42 £76.17 |
| 15 mg | $11.50 £9.09 | $115.00 £90.85 |
Handling
How should DSIP be stored and reconstituted?
Full explanation of why each of these matters: peptide handling and storage reference.
Research Context
What is DSIP researched for?
Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what DSIP does, and nothing here is a statement that it is safe or effective for any purpose.
Sleep architecture research
DSIP was named after its discovery in the blood of sleeping rabbits, and early studies examined whether it increased slow-wave sleep. Results across laboratories were inconsistent, which is a large part of why interest faded. 12
Stress and hormone response
Some studies report effects on corticotropin and other hypothalamic-pituitary-adrenal hormones, and this has been a secondary line of investigation.
An honest caveat
Despite the name, DSIP has never been established as a sleep-regulating hormone. It remains a peptide of uncertain function, which is exactly why it still appears in exploratory research rather than clinical development. 3
References
- 1The influence of synthetic DSIP (delta-sleep-inducing-peptide) on disturbed human sleep. Experientia (1981). PMID 7028502
- 2Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients. A double-blind study. Neuropsychobiology (1992). PMID 1299794
- 3Delta sleep-inducing peptide (DSIP): a still unresolved riddle. J Neurochem (2006). PMID 16539679
Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.
Applications
Where DSIP is used in the laboratory
- Sleep and circadian regulation research in animal and cell models
- Neuropeptide receptor binding studies
- Peptide stability research in biological buffers
- Analytical method development for small regulatory peptides
Verification
Does DSIP come with a COA?
Yes — every box. Each batch of DSIP is analysed by Janoshik Analytical or Freedom Diagnostic. The certificate confirms identity by mass spectrometry and purity by HPLC, and is tied to the batch number printed on the vial label. You can ask to see it before you order.
Example COA. You receive the certificate matching your own batch.
Questions
DSIP questions, answered
Why is DSIP called delta sleep-inducing peptide?
The name comes from the circumstances of its discovery rather than a confirmed mechanism. It was isolated from cerebral venous blood during delta-wave sleep in early research. The name has persisted, but the peptide remains under investigation and its endogenous role is not settled.
How much does DSIP cost?
DSIP starts at $7.79 per vial, sold in boxes of 10 vials at $77.85 per box (about £61.50). 3 strengths available: 5 mg, 10 mg, 15 mg. There is no minimum order.
What purity is your DSIP?
All batches test at 99%+ purity. Every box ships with a batch-specific Certificate of Analysis from Janoshik Analytical or Freedom Diagnostic, confirming identity by mass spectrometry and purity by HPLC.
Is there a minimum order for DSIP?
No. You can order a single box of 10 vials. There is no trade account, bulk commitment or minimum spend.
How is DSIP shipped?
Tracked and in discreet, plain packaging, dispatched within 1–3 working days. Delivery estimates are UK 5–7 working days, EU 8–10, USA 5–8 and rest of world 10–12. Full detail is on the shipping page.
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