


Cagrilintide + Semaglutide (CagriSema) Peptide Vials
Research blend: cagrilintide and semaglutide co-lyophilised in one vial at a 1:1 ratio · boxes of 10 vials
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Strength 3 options · price per box
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- No minimumBoxes of 10 vials
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Often ordered together


One box of each. Change strengths or quantities in the cart.
Also ordered with Cagrilintide + Semaglutide (CagriSema)
About Cagrilintide + Semaglutide (CagriSema)
What is Cagrilintide + Semaglutide (CagriSema)?
Overview
What is Cagrilintide + Semaglutide (CagriSema)?
This is a research blend of two peptides in one vial: cagrilintide, a long-acting amylin analogue, and semaglutide, a GLP-1 receptor agonist. CagriSema is the name this pairing carries in Novo Nordisk's clinical programme; we use it only to identify the combination, and this preparation is not that company's product. The two peptides act through different hormone systems, which is the case for combining them. Supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
Cagrilintide + Semaglutide (CagriSema) at a glance
| Compound | Cagrilintide + Semaglutide (CagriSema) |
|---|---|
| Also known as | CagriSema, Cagri Sema, Cagri-Sema, cagrilintide semaglutide blend, cagrilintide and semaglutide |
| Classification | Research blend: cagrilintide and semaglutide co-lyophilised in one vial at a 1:1 ratio |
| Purity | 99%+ by HPLC |
| Physical form | Lyophilised powder |
| Available strengths | Cagrilintide 2.5 mg + Semaglutide 2.5 mg, Cagrilintide 5 mg + Semaglutide 5 mg, Cagrilintide 10 mg + Semaglutide 10 mg |
| Box quantity | 10 vials |
| Price from | $9.93 per vial ($99.25 per box) |
| Research status | The cagrilintide and semaglutide combination has phase 2 data in type 2 diabetes and phase 3 data in overweight and obesity, both published in major journals. Each component also has its own trial record. |
| Documentation | Batch-specific third-party COA |
These are catalogue target specifications, not batch results. The 99%+ purity figure is the specification we buy to. The authoritative figures for any particular box are the ones printed on that box’s Certificate of Analysis, which is lot-specific. What research grade actually means explains the difference. Terms such as HPLC purity and net peptide content are explained in the peptide glossary.
We make no “third-party verified” claim for a batch unless the matching report is supplied with it. Ask for the current COA for the lot in stock before you order — we will send it.
Prices for every strength
Pricing
How much does Cagrilintide + Semaglutide (CagriSema) cost?
Cagrilintide + Semaglutide (CagriSema) starts at $9.93 per vial (£7.44), sold in boxes of 10 at $99.25. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.
| Strength | Per vial | Box of 10 |
|---|---|---|
| Cagrilintide 2.5 mg + Semaglutide 2.5 mg | $9.93 £7.44 | $99.25 £74.36 |
| Cagrilintide 5 mg + Semaglutide 5 mg | $13.79 £10.33 | $137.85 £103.28 |
| Cagrilintide 10 mg + Semaglutide 10 mg | $16.08 £12.05 | $160.81 £120.48 |
Storage & reconstitution
Handling
How should Cagrilintide + Semaglutide (CagriSema) be stored and reconstituted?
Sealed vials tolerate ambient temperature in transit and keep at −20 °C beyond that. Reconstitute slowly down the vial wall, swirl rather than shake, then refrigerate at 2–8 °C and aliquot before freezing.
Why each of those matters, and what a freeze–thaw cycle actually costs: peptide handling and storage reference. How long a mixed vial keeps: reconstituted peptide shelf life.
What it is researched for
Research Context
What is Cagrilintide + Semaglutide (CagriSema) researched for?
Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what Cagrilintide + Semaglutide (CagriSema) does, and nothing here is a statement that it is safe or effective for any purpose.
What the trials found
A phase 2 trial in type 2 diabetes compared the combination with each peptide alone and reported greater reductions in HbA1c and body weight with the combination. A phase 3 trial in adults with overweight or obesity reported greater weight reduction with the combination than with either peptide alone or placebo. 12
Why amylin and GLP-1 are combined
Amylin and GLP-1 reduce food intake through different receptor systems, so pairing them aims at an additive effect without raising the dose of either. The trials above are the test of that rationale. 12
What is not established
Long-term outcome and safety data beyond the trial periods is not yet available. The trials gave the two peptides as a co-administered injection; how a co-lyophilised research blend compares on stability has not been published.
References
- 1Efficacy and safety of co-administered once-weekly cagrilintide 2.4 mg with once-weekly semaglutide 2.4 mg in type 2 diabetes: a multicentre, randomised, double-blind, active-controlled, phase 2 trial. Lancet (2023). PMID 37364590
- 2Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity. N Engl J Med (2025). PMID 40544433
Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.
Laboratory uses
Applications
Where Cagrilintide + Semaglutide (CagriSema) is used in the laboratory
- Amylin and GLP-1 co-agonism, the pairing that has reached phase 3 as a fixed combination
- Comparative work against cagrilintide and semaglutide on their own, both stocked separately in this catalogue
- Dose research at a fixed ratio: all three strengths keep the 1:1 ratio used in the published trials, so the amount changes and the ratio does not
- Comparison with single-molecule multi-receptor agonists such as tirzepatide and retatrutide
Batch COA
Verification
Does Cagrilintide + Semaglutide (CagriSema) come with a COA?
Yes — every box. Each batch of Cagrilintide + Semaglutide (CagriSema) is analysed by an independent third-party laboratory, and the certificate is tied to the batch number on the vial label.
Example COA. You receive the certificate matching your own batch.
Questions & answers
Questions
Cagrilintide + Semaglutide (CagriSema) questions, answered
What is CagriSema?
CagriSema is the clinical-programme name for cagrilintide combined with semaglutide. It is not a single molecule: two separate peptides are used together. In our vials the two are co-lyophilised at a 1:1 ratio, and each strength lists the amount of each peptide.
Why buy the blend rather than cagrilintide and semaglutide separately?
The peptides are the same; the difference is preparation. A premixed vial fixes the ratio and means one reconstitution instead of two. Separate vials let you change the ratio. We stock both, so choose the separate peptides if your protocol needs a ratio other than 1:1.
Is CagriSema approved?
No. The combination is investigational and is not approved for any use in any country. Semaglutide on its own is a licensed medicine in some countries, but the research material sold here is not a medicine and is not for human consumption.
How much does Cagrilintide + Semaglutide (CagriSema) cost?
Cagrilintide + Semaglutide (CagriSema) starts at $9.93 per vial, sold in boxes of 10 vials at $99.25 per box (about £74.36). 3 strengths available: Cagrilintide 2.5 mg + Semaglutide 2.5 mg, Cagrilintide 5 mg + Semaglutide 5 mg, Cagrilintide 10 mg + Semaglutide 10 mg. There is no minimum order.
How is Cagrilintide + Semaglutide (CagriSema) shipped to the UK and USA?
Tracked to the UK, USA, EU and worldwide, in plain packaging, dispatched within 1–2 working days. Country-by-country estimates are on the shipping page.
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