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Metabolic & Weight Research In stock · dispatched in 1–2 working days

5-Amino-1MQ Research Vials

Small-molecule quinolinium inhibitor of nicotinamide N-methyltransferase · 5mg–50mg · boxes of 10 vials

$65.85 £49.33 per box of 10 vials
$6.59 per vial · £4.94 · £0.99 per mg
$80.42 £60.25 per box of 10 vials
$8.04 per vial · £6.02 · £0.60 per mg
$89.31 £66.91 per box of 10 vials
$8.93 per vial · £6.69 · £0.33 per mg
$95.71 £71.71 per box of 10 vials
$9.57 per vial · £7.17 · £0.14 per mg

Free delivery worldwide on orders over $1,000 (about £749)

Strength 4 options · price per box

Lab report for this strengthSent free on WhatsApp on request

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Boxes

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  • No minimumBoxes of 10 vials
  • Tracked shippingDispatched in 1–2 working days
  • Batch COAFree on request
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Often ordered together

5-Amino-1MQ 5 mg$65.85 / box
Bacteriostatic Water 3 mL$9.00 / box
2 boxes, 20 vials$74.85

One box of each. Change strengths or quantities in the cart.

About 5-Amino-1MQ

What is 5-Amino-1MQ?

Overview

What is 5-Amino-1MQ?

5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase, the enzyme that methylates nicotinamide and by doing so removes it from the salvage pathway that regenerates NAD+. It is a quinolinium compound, not a peptide, and is catalogued here because it is ordered alongside the metabolic peptides rather than because it shares their structure. Supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.

Laboratory research use onlyNobelPepLab supplies 5-Amino-1MQ strictly for in vitro and laboratory research. We do not provide dosing guidance, do not make health claims, and do not supply products for human or veterinary use.

5-Amino-1MQ at a glance

5-Amino-1MQ specifications
Compound5-Amino-1MQ
Also known as5-amino-1-methylquinolinium, 5A1MQ, 5 amino 1MQ, NNMT inhibitor
ClassificationSmall-molecule quinolinium inhibitor of nicotinamide N-methyltransferase
CAS number685079-15-6
Molecular formulaC10H11N2+
Molecular weight159.21 g/mol
PubChem CID950107
Purity99%+ by HPLC
Physical formLyophilised powder
Available strengths5 mg, 10 mg, 20 mg, 50 mg
Box quantity10 vials
Price from$6.59 per vial ($65.85 per box)
Research status5-Amino-1MQ inhibits nicotinamide N-methyltransferase. The interest in it is indirect: NNMT consumes nicotinamide, so inhibiting the enzyme is one proposed route to raising NAD+ without supplying a precursor. The work is preclinical, mostly cell and rodent models, and the field is young.
DocumentationBatch-specific third-party COA

These are catalogue target specifications, not batch results. The 99%+ purity figure is the specification we buy to. The authoritative figures for any particular box are the ones printed on that box’s Certificate of Analysis, which is lot-specific. What research grade actually means explains the difference. Terms such as HPLC purity and net peptide content are explained in the peptide glossary.

We make no “third-party verified” claim for a batch unless the matching report is supplied with it. Ask for the current COA for the lot in stock before you order — we will send it.

Prices for every strength

Pricing

5-Amino-1MQ price per vial: 5mg, 10mg, 20mg to 50mg

5-Amino-1MQ starts at $6.59 per vial (£4.94), sold in boxes of 10 at $65.85. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.

5-Amino-1MQ price by strength. Billed in USD; GBP shown for reference. Each box contains 10 vials.
StrengthPer vialBox of 10
5 mg$6.59 £4.94$65.85 £49.33
10 mg$8.04 £6.02$80.42 £60.25
20 mg$8.93 £6.69$89.31 £66.91
50 mg$9.57 £7.17$95.71 £71.71
Important: Preclinical. No approved use in any country, no completed human trials, and not for human consumption.
Storage & reconstitution

Handling

How should 5-Amino-1MQ be stored and reconstituted?

Sealed vials tolerate ambient temperature in transit and keep at −20 °C beyond that. Reconstitute slowly down the vial wall, swirl rather than shake, then refrigerate at 2–8 °C and aliquot before freezing.

What it is researched for

Research Context

What is 5-Amino-1MQ researched for?

Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what 5-Amino-1MQ does, and nothing here is a statement that it is safe or effective for any purpose.

Research status 5-Amino-1MQ inhibits nicotinamide N-methyltransferase. The interest in it is indirect: NNMT consumes nicotinamide, so inhibiting the enzyme is one proposed route to raising NAD+ without supplying a precursor. The work is preclinical, mostly cell and rodent models, and the field is young.

The enzyme and why it is a target

NNMT methylates nicotinamide, diverting it from the salvage pathway that regenerates NAD+. Elevated NNMT expression has been reported in adipose tissue and linked to metabolic pathways, which is the basis for treating the enzyme as a therapeutic target rather than a housekeeping one. 1

Where the field has reached

Reviews of NNMT inhibitor development describe a field moving from tool compounds toward candidates that might be tested clinically, while noting that none has yet made that transition. 2

What is not established

No NNMT inhibitor has completed a human trial. Whether inhibiting the enzyme raises NAD+ meaningfully in humans, and whether that produces the metabolic effects seen in rodents, is untested.

References

  1. 1Exploring NNMT: from metabolic pathways to therapeutic targets. Arch Pharm Res (2024). PMID 39604638
  2. 2Emerging opportunities for nicotinamide N-methyltransferase (NNMT) inhibitor clinical translation. Trends Pharmacol Sci (2026). PMID 42067476

Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.

Read this before citing any of the abovePreclinical means the work was done in cells or animals. Results in those systems very often fail to reproduce in humans. NobelPepLab supplies 5-Amino-1MQ for laboratory research only, does not provide dosing guidance, and does not supply products for human or veterinary use.
Laboratory uses

Applications

Where 5-Amino-1MQ is used in the laboratory

  • NNMT enzyme inhibition studies, the direct target
  • NAD+ salvage pathway research, since inhibiting NNMT is one proposed route to raising cellular NAD+ without supplying a precursor
  • Adipocyte metabolism models, the tissue in which NNMT inhibition has been examined most
  • Comparative work alongside NAD+ itself, which is in this catalogue
Batch COA

Verification

Does 5-Amino-1MQ come with a COA?

Yes — every box. Each batch of 5-Amino-1MQ is analysed by an independent third-party laboratory, and the certificate is tied to the batch number on the vial label.

Example Certificate of Analysis, not the certificate for this batch

Example COA. You receive the certificate matching your own batch.

Questions & answers

Questions

5-Amino-1MQ questions, answered

Is 5-Amino-1MQ a peptide?

No. It is a small-molecule quinolinium salt weighing about 159 g/mol, roughly a twentieth of the smallest peptide in this catalogue. It appears here because researchers ordering metabolic peptides frequently order it in the same box, not because it belongs to the same chemical class. We would rather say that plainly than let the catalogue imply otherwise.

How much does 5-Amino-1MQ cost?

5-Amino-1MQ starts at $6.59 per vial, sold in boxes of 10 vials at $65.85 per box (about £49.33). 4 strengths available: 5 mg, 10 mg, 20 mg, 50 mg. There is no minimum order.

Can I buy 5-Amino-1MQ 10mg vials in the UK?

Yes. 5-Amino-1MQ 10mg comes in boxes of 10 vials at $80.42 per box ($8.04 per vial, about £60.25 per box), sent tracked to UK addresses. There is no minimum order.

How is 5-Amino-1MQ shipped to the UK and USA?

Tracked to the UK, USA, EU and worldwide, in plain packaging, dispatched within 1–2 working days. Country-by-country estimates are on the shipping page.