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N-acetylated 28-residue peptide
Thymosin Alpha-1
Thymosin Alpha-1 is a 28-residue N-acetylated peptide originally isolated from thymic tissue, where it forms part of the thymosin fraction 5 preparation. It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
$105.00 (£82.95) per box of 10 vials · 5 mg, 10 mg
Overview
What is Thymosin Alpha-1?
Thymosin Alpha-1 is a 28-residue N-acetylated peptide originally isolated from thymic tissue, where it forms part of the thymosin fraction 5 preparation. It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
Thymosin Alpha-1 at a glance
| Compound | Thymosin Alpha-1 |
|---|---|
| Also known as | Thymalfasin, Talpha1, Ta1, Thymosin a1 |
| Classification | N-acetylated 28-residue peptide |
| CAS number | 62304-98-7 |
| Molecular formula | C129H215N33O55 |
| Molecular weight | 3108.3 g/mol |
| Sequence | 28-residue N-acetylated sequence, Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN |
| Purity | 99%+ by HPLC |
| Physical form | Lyophilised powder |
| Available strengths | 5 mg, 10 mg |
| Box quantity | 10 vials |
| Price from | $10.50 per vial ($105.00 per box) |
| Research status | An approved medicine in over 30 countries under the name thymalfasin. Not approved in the UK or US. |
| Documentation | Batch-specific COA (Janoshik or Freedom Diagnostic) |
Nominal specifications. The authoritative figures for any given box are those printed on its batch COA.
Pricing
How much does Thymosin Alpha-1 cost?
Thymosin Alpha-1 starts at $10.50 per vial (£8.30), sold in boxes of 10 at $105.00. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.
| Strength | Per vial | Box of 10 |
|---|---|---|
| 5 mg | $10.50 £8.30 | $105.00 £82.95 |
| 10 mg | $16.07 £12.70 | $160.71 £126.96 |
Handling
How should Thymosin Alpha-1 be stored and reconstituted?
Full explanation of why each of these matters: peptide handling and storage reference.
Research Context
What is Thymosin Alpha-1 researched for?
Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what Thymosin Alpha-1 does, and nothing here is a statement that it is safe or effective for any purpose.
Toll-like receptor signalling
Thymosin Alpha-1 acts on TLR2 and TLR9 on immune cells, influencing how strongly those cells respond to pathogen-associated signals. This is the best-characterised part of its mechanism.
T-cell maturation
It was originally isolated from thymic tissue, the organ where T-cells mature, and research examines its influence on that maturation process and on the balance of T-cell subsets.
References
- 1The efficacy of thymosin alpha 1 for severe sepsis (ETASS): a multicenter, single-blind, randomized and controlled trial. Crit Care (2013). PMC4056079
- 2Efficacy of thymosin alpha 1 for sepsis: a systematic review and meta-analysis of randomized controlled trials. Front Cell Infect Microbiol (2025). PMID 40969554
Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.
Applications
Where Thymosin Alpha-1 is used in the laboratory
- Toll-like receptor signalling studies in immune cell culture
- T-cell maturation and differentiation research
- Comparative studies within the thymosin peptide family
- Analytical characterisation of N-acetylated peptides
Verification
Does Thymosin Alpha-1 come with a COA?
Yes — every box. Each batch of Thymosin Alpha-1 is analysed by Janoshik Analytical or Freedom Diagnostic. The certificate confirms identity by mass spectrometry and purity by HPLC, and is tied to the batch number printed on the vial label. You can ask to see it before you order.
Example COA. You receive the certificate matching your own batch.
Questions
Thymosin Alpha-1 questions, answered
How is Thymosin Alpha-1 different from Thymosin Beta-4?
They share a name but little else. Thymosin Alpha-1 is a 28-residue N-acetylated peptide studied in immune signalling. Thymosin Beta-4 is a 43-residue actin-binding peptide studied in cytoskeletal dynamics and cell migration. Both were first isolated from the same thymic extract, which is the only real reason they share a family name.
How much does Thymosin Alpha-1 cost?
Thymosin Alpha-1 starts at $10.50 per vial, sold in boxes of 10 vials at $105.00 per box (about £82.95). 2 strengths available: 5 mg, 10 mg. There is no minimum order.
What purity is your Thymosin Alpha-1?
All batches test at 99%+ purity. Every box ships with a batch-specific Certificate of Analysis from Janoshik Analytical or Freedom Diagnostic, confirming identity by mass spectrometry and purity by HPLC.
Is there a minimum order for Thymosin Alpha-1?
No. You can order a single box of 10 vials. There is no trade account, bulk commitment or minimum spend.
How is Thymosin Alpha-1 shipped?
Tracked and in discreet, plain packaging, dispatched within 1–3 working days. Delivery estimates are UK 5–7 working days, EU 8–10, USA 5–8 and rest of world 10–12. Full detail is on the shipping page.
Catalog
