All products are for laboratory research purposes only. Not for human consumption.
Decapeptide agonist at KISS1R (GPR54)
Kisspeptin-10
Kisspeptin-10 is the ten-residue C-terminal fragment of kisspeptin, the peptide product of the KISS1 gene, and acts as an agonist at the KISS1R receptor (also called GPR54). It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
$87.14 (£68.84) per box of 10 vials · 5 mg, 10 mg
Overview
What is Kisspeptin-10?
Kisspeptin-10 is the ten-residue C-terminal fragment of kisspeptin, the peptide product of the KISS1 gene, and acts as an agonist at the KISS1R receptor (also called GPR54). It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
Kisspeptin-10 at a glance
| Compound | Kisspeptin-10 |
|---|---|
| Also known as | Metastin 45-54, KP-10, Kisspeptin 112-121 |
| Classification | Decapeptide agonist at KISS1R (GPR54) |
| CAS number | 374675-21-5 |
| Molecular formula | C63H83N17O14 |
| Molecular weight | 1302.45 g/mol |
| Sequence | Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 |
| Purity | 99%+ by HPLC |
| Physical form | Lyophilised powder |
| Available strengths | 5 mg, 10 mg |
| Box quantity | 10 vials |
| Price from | $8.71 per vial ($87.14 per box) |
| Research status | Not approved. Actively studied in registered academic clinical trials, particularly in reproductive endocrinology. |
| Documentation | Batch-specific COA (Janoshik or Freedom Diagnostic) |
Nominal specifications. The authoritative figures for any given box are those printed on its batch COA.
Pricing
How much does Kisspeptin-10 cost?
Kisspeptin-10 starts at $8.71 per vial (£6.88), sold in boxes of 10 at $87.14. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.
| Strength | Per vial | Box of 10 |
|---|---|---|
| 5 mg | $8.71 £6.88 | $87.14 £68.84 |
| 10 mg | $10.07 £7.96 | $100.71 £79.56 |
Handling
How should Kisspeptin-10 be stored and reconstituted?
Full explanation of why each of these matters: peptide handling and storage reference.
Research Context
What is Kisspeptin-10 researched for?
Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what Kisspeptin-10 does, and nothing here is a statement that it is safe or effective for any purpose.
Reproductive axis control
Kisspeptin sits at the top of the reproductive hormone cascade. It acts on KISS1R receptors on GnRH neurons, which in turn drive LH and FSH release from the pituitary. Loss-of-function mutations in KISS1R prevent puberty entirely, which is how its importance was discovered. 1
Fertility research
Academic clinical studies have examined kisspeptin as a way to trigger egg maturation with a different risk profile from existing methods. This is among the more advanced human research programmes for any peptide in this catalog. 2
Original discovery as metastin
The same gene product was independently identified as a suppressor of cancer metastasis and named metastin. The reproductive role was found later, and both names remain in use in the literature.
References
- 1Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men. J Clin Endocrinol Metab (2011). PMID 21632807
- 2The effects of kisspeptin-10 on reproductive hormone release show sexual dimorphism in humans. J Clin Endocrinol Metab (2011). PMID 21976724
Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.
Applications
Where Kisspeptin-10 is used in the laboratory
- KISS1R and GPR54 receptor binding and signalling studies
- Reproductive neuroendocrinology research in animal models
- GnRH neuron signalling studies
- Comparative work against longer kisspeptin fragments
Verification
Does Kisspeptin-10 come with a COA?
Yes — every box. Each batch of Kisspeptin-10 is analysed by Janoshik Analytical or Freedom Diagnostic. The certificate confirms identity by mass spectrometry and purity by HPLC, and is tied to the batch number printed on the vial label. You can ask to see it before you order.
Example COA. You receive the certificate matching your own batch.
Questions
Kisspeptin-10 questions, answered
Why is Kisspeptin-10 also called Metastin 45-54?
The KISS1 gene product was independently characterised as a metastasis-suppressor protein and named metastin. Kisspeptin-10 corresponds to residues 45 to 54 of that protein, so both names refer to the same ten-residue fragment. You will see either used in the literature.
How much does Kisspeptin-10 cost?
Kisspeptin-10 starts at $8.71 per vial, sold in boxes of 10 vials at $87.14 per box (about £68.84). 2 strengths available: 5 mg, 10 mg. There is no minimum order.
What purity is your Kisspeptin-10?
All batches test at 99%+ purity. Every box ships with a batch-specific Certificate of Analysis from Janoshik Analytical or Freedom Diagnostic, confirming identity by mass spectrometry and purity by HPLC.
Is there a minimum order for Kisspeptin-10?
No. You can order a single box of 10 vials. There is no trade account, bulk commitment or minimum spend.
How is Kisspeptin-10 shipped?
Tracked and in discreet, plain packaging, dispatched within 1–3 working days. Delivery estimates are UK 5–7 working days, EU 8–10, USA 5–8 and rest of world 10–12. Full detail is on the shipping page.
