All products are for laboratory research purposes only. Not for human consumption.
Synthetic fragment of Thymosin Beta-4
TB-500
TB-500 is a synthetic acetylated seven-residue fragment (Ac-LKKTETQ) corresponding to the actin-binding domain of Thymosin Beta-4. It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
$141.92 (£112.12) per box of 10 vials · 10 mg
Overview
What is TB-500?
TB-500 is a synthetic acetylated seven-residue fragment (Ac-LKKTETQ) corresponding to the actin-binding domain of Thymosin Beta-4. It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
TB-500 at a glance
| Compound | TB-500 |
|---|---|
| Also known as | TB500, Thymosin Beta-4 fragment, Ac-LKKTETQ, Thymosin B4 |
| Classification | Synthetic fragment of Thymosin Beta-4 |
| CAS number | 885340-08-9 |
| Molecular formula | C37H64N10O13 |
| Molecular weight | ~889.0 g/mol |
| Sequence | Ac-LKKTETQ (acetylated 7-residue active fragment) |
| Purity | 99%+ by HPLC |
| Physical form | Lyophilised powder |
| Available strengths | 10 mg |
| Box quantity | 10 vials |
| Price from | $14.19 per vial ($141.92 per box) |
| Research status | Preclinical. Full-length Thymosin Beta-4 has been through early clinical trials; the fragment has not. Prohibited in competitive sport under the WADA S2 category. |
| Documentation | Batch-specific COA (Janoshik or Freedom Diagnostic) |
Nominal specifications. The authoritative figures for any given box are those printed on its batch COA.
Pricing
How much does TB-500 cost?
TB-500 starts at $14.19 per vial (£11.21), sold in boxes of 10 at $141.92. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.
| Strength | Per vial | Box of 10 |
|---|---|---|
| 10 mg | $14.19 £11.21 | $141.92 £112.12 |
Handling
How should TB-500 be stored and reconstituted?
Full explanation of why each of these matters: peptide handling and storage reference.
Research Context
What is TB-500 researched for?
Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what TB-500 does, and nothing here is a statement that it is safe or effective for any purpose.
Actin binding and cell movement
The LKKTETQ sequence is the region of Thymosin Beta-4 that binds actin, the filament protein that gives cells their shape and allows them to move. By holding actin monomers in reserve it changes how quickly cells can reorganise and migrate. 1
Wound and tissue repair models
Cell migration is the first step in closing a wound, which is why most research uses scratch assays and animal wound models. Full-length Thymosin Beta-4 reached early clinical trials for corneal and skin wounds. 12
Cardiac and vascular research
Thymosin Beta-4 has been studied in models of heart injury, where it appears to influence the behaviour of cells in the outer layer of the heart. 2
References
- 1Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues. Trends Mol Med (2005). PMID 16099219
- 2The actin binding site on thymosin beta4 promotes angiogenesis. FASEB J (2003). PMID 14500546
Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.
Compare TB-500
Applications
Where TB-500 is used in the laboratory
- Actin sequestration and cytoskeletal dynamics studies
- Cell migration and in vitro wound-model research
- Comparative studies against full-length Thymosin Beta-4
- Peptide fragment structure-activity research
Verification
Does TB-500 come with a COA?
Yes — every box. Each batch of TB-500 is analysed by Janoshik Analytical or Freedom Diagnostic. The certificate confirms identity by mass spectrometry and purity by HPLC, and is tied to the batch number printed on the vial label. You can ask to see it before you order.
Example COA. You receive the certificate matching your own batch.
Questions
TB-500 questions, answered
Is TB-500 the same as Thymosin Beta-4?
Not necessarily, and this is worth checking carefully. TB-500 most commonly refers to the acetylated seven-residue fragment Ac-LKKTETQ (around 889 g/mol), whereas full-length Thymosin Beta-4 is a 43-residue peptide of around 4963 g/mol. Different suppliers use the name for different molecules. Always confirm which form you have received against the molecular weight stated on the batch COA.
How much does TB-500 cost?
TB-500 starts at $14.19 per vial, sold in boxes of 10 vials at $141.92 per box (about £112.12). 1 strength available: 10 mg. There is no minimum order.
What purity is your TB-500?
All batches test at 99%+ purity. Every box ships with a batch-specific Certificate of Analysis from Janoshik Analytical or Freedom Diagnostic, confirming identity by mass spectrometry and purity by HPLC.
Is there a minimum order for TB-500?
No. You can order a single box of 10 vials. There is no trade account, bulk commitment or minimum spend.
How is TB-500 shipped?
Tracked and in discreet, plain packaging, dispatched within 1–3 working days. Delivery estimates are UK 5–7 working days, EU 8–10, USA 5–8 and rest of world 10–12. Full detail is on the shipping page.
