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Selective ghrelin receptor (GHS-R1a) agonist pentapeptide
Ipamorelin
Ipamorelin is a synthetic pentapeptide that acts as a selective agonist at the growth hormone secretagogue receptor (GHS-R1a). It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
$79.71 (£62.97) per box of 10 vials · 5 mg, 10 mg
Overview
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide that acts as a selective agonist at the growth hormone secretagogue receptor (GHS-R1a). It is supplied as a lyophilised powder in sealed vials, boxed in tens, for laboratory research use only.
Ipamorelin at a glance
| Compound | Ipamorelin |
|---|---|
| Also known as | NNC 26-0161, Ipamorelin acetate, IPAM |
| Classification | Selective ghrelin receptor (GHS-R1a) agonist pentapeptide |
| CAS number | 170851-70-4 |
| Molecular formula | C38H49N9O5 |
| Molecular weight | 711.85 g/mol |
| Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH2 |
| Purity | 99%+ by HPLC |
| Physical form | Lyophilised powder |
| Available strengths | 5 mg, 10 mg |
| Box quantity | 10 vials |
| Price from | $7.97 per vial ($79.71 per box) |
| Research status | Preclinical and early clinical. Trials were conducted and discontinued. Not approved. Prohibited in competitive sport under the WADA S2 category. |
| Documentation | Batch-specific COA (Janoshik or Freedom Diagnostic) |
Nominal specifications. The authoritative figures for any given box are those printed on its batch COA.
Pricing
How much does Ipamorelin cost?
Ipamorelin starts at $7.97 per vial (£6.30), sold in boxes of 10 at $79.71. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.
| Strength | Per vial | Box of 10 |
|---|---|---|
| 5 mg | $7.97 £6.30 | $79.71 £62.97 |
| 10 mg | $9.46 £7.47 | $94.57 £74.71 |
Handling
How should Ipamorelin be stored and reconstituted?
Full explanation of why each of these matters: peptide handling and storage reference.
Research Context
What is Ipamorelin researched for?
Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what Ipamorelin does, and nothing here is a statement that it is safe or effective for any purpose.
Selective receptor activation
Ipamorelin binds the ghrelin receptor GHS-R1a with unusually little activity elsewhere. Earlier compounds in the same class also raised cortisol and prolactin; Ipamorelin largely does not, which makes it a cleaner tool for isolating a single pathway. 1
Growth hormone pulse research
Because it acts through a different receptor from GHRH analogues, it is used to study how two independent signals combine to shape the natural pulsing pattern of growth hormone release. 2
Gastrointestinal motility
Ghrelin receptor agonists influence gut movement, and Ipamorelin was investigated in a clinical trial for post-operative ileus before development stopped. 1
References
- 1Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol (1998). PMID 9849822
- 2Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Pharm Res (1999). PMID 10496658
Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.
Applications
Where Ipamorelin is used in the laboratory
- GHS-R1a receptor selectivity and binding affinity studies
- Comparative research against non-selective secretagogues such as GHRP-6
- Somatotroph signalling and calcium flux assays
- Receptor pharmacology method development
Verification
Does Ipamorelin come with a COA?
Yes — every box. Each batch of Ipamorelin is analysed by Janoshik Analytical or Freedom Diagnostic. The certificate confirms identity by mass spectrometry and purity by HPLC, and is tied to the batch number printed on the vial label. You can ask to see it before you order.
Example COA. You receive the certificate matching your own batch.
Questions
Ipamorelin questions, answered
How is Ipamorelin different from other growth hormone secretagogues?
Ipamorelin is notable for its selectivity at GHS-R1a. Earlier secretagogues such as GHRP-6 and GHRP-2 show broader cross-reactivity at other receptors, which makes Ipamorelin a common choice as a comparatively clean reference compound in receptor selectivity studies.
How much does Ipamorelin cost?
Ipamorelin starts at $7.97 per vial, sold in boxes of 10 vials at $79.71 per box (about £62.97). 2 strengths available: 5 mg, 10 mg. There is no minimum order.
What purity is your Ipamorelin?
All batches test at 99%+ purity. Every box ships with a batch-specific Certificate of Analysis from Janoshik Analytical or Freedom Diagnostic, confirming identity by mass spectrometry and purity by HPLC.
Is there a minimum order for Ipamorelin?
No. You can order a single box of 10 vials. There is no trade account, bulk commitment or minimum spend.
How is Ipamorelin shipped?
Tracked and in discreet, plain packaging, dispatched within 1–3 working days. Delivery estimates are UK 5–7 working days, EU 8–10, USA 5–8 and rest of world 10–12. Full detail is on the shipping page.
Catalog
