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Synthetic growth-hormone-releasing hormone analogue (29 residues)
CJC-1295
CJC-1295 is a synthetic analogue of growth-hormone-releasing hormone based on the GHRH(1-29) fragment, carrying four amino acid substitutions that increase resistance to enzymatic degradation. We stock three forms: without DAC (also sold as Modified GRF 1-29), with DAC (a drug affinity complex that extends half-life via albumin binding), and a CJC-1295 with Ipamorelin blend.
$105.71 (£83.51) per box of 10 vials · 5 mg (no DAC), 10 mg (no DAC), 2 mg (with DAC), 5 mg (with DAC), 10 mg (with DAC), 5 mg + 5 mg (CJC-1295 + Ipamorelin)
Overview
What is CJC-1295?
CJC-1295 is a synthetic analogue of growth-hormone-releasing hormone based on the GHRH(1-29) fragment, carrying four amino acid substitutions that increase resistance to enzymatic degradation. We stock three forms: without DAC (also sold as Modified GRF 1-29), with DAC (a drug affinity complex that extends half-life via albumin binding), and a CJC-1295 with Ipamorelin blend.
CJC-1295 at a glance
| Compound | CJC-1295 |
|---|---|
| Also known as | Modified GRF 1-29, Mod GRF 1-29, CJC1295, CJC-1295 DAC, Tetrasubstituted GRF 1-29 |
| Classification | Synthetic growth-hormone-releasing hormone analogue (29 residues) |
| CAS number | 863288-34-0 |
| Molecular formula | C152H252N44O42 |
| Molecular weight | 3367.9 g/mol (without DAC) |
| Sequence | Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2 |
| Purity | 99%+ by HPLC |
| Physical form | Lyophilised powder |
| Available strengths | 5 mg (no DAC), 10 mg (no DAC), 2 mg (with DAC), 5 mg (with DAC), 10 mg (with DAC), 5 mg + 5 mg (CJC-1295 + Ipamorelin) |
| Box quantity | 10 vials |
| Price from | $10.57 per vial ($105.71 per box) |
| Research status | Preclinical and early clinical. The DAC form reached Phase 2 trials and was discontinued. Not approved. Prohibited in competitive sport under the WADA S2 category. |
| Documentation | Batch-specific COA (Janoshik or Freedom Diagnostic) |
Nominal specifications. The authoritative figures for any given box are those printed on its batch COA.
Pricing
How much does CJC-1295 cost?
CJC-1295 starts at $10.57 per vial (£8.35), sold in boxes of 10 at $105.71. One box is the smallest order and there is no trade account or minimum spend. Larger volumes are negotiable.
| Strength | Per vial | Box of 10 |
|---|---|---|
| 5 mg (no DAC) | $10.57 £8.35 | $105.71 £83.51 |
| 10 mg (no DAC) | $14.51 £11.46 | $145.14 £114.66 |
| 2 mg (with DAC) | $11.00 £8.69 | $110.00 £86.90 |
| 5 mg (with DAC) | $15.50 £12.25 | $155.00 £122.45 |
| 10 mg (with DAC) | $26.24 £20.73 | $262.35 £207.26 |
| 5 mg + 5 mg (CJC-1295 + Ipamorelin) | $12.43 £9.82 | $124.28 £98.18 |
Handling
How should CJC-1295 be stored and reconstituted?
Full explanation of why each of these matters: peptide handling and storage reference.
Research Context
What is CJC-1295 researched for?
Below is a plain-English summary of what published research has investigated, and what it has found. These are descriptions of research activity and published results. They are not claims about what CJC-1295 does, and nothing here is a statement that it is safe or effective for any purpose.
Growth hormone release
CJC-1295 mimics GHRH, the hypothalamic signal that tells the pituitary to release growth hormone. Native GHRH is destroyed within minutes; four amino acid substitutions let this analogue survive long enough to study. 1
DAC versus non-DAC half-life
The DAC version binds covalently to albumin in blood, extending its presence from hours to days. Comparing the two forms is one of the cleanest available ways to study how half-life alone changes a hormonal signalling pattern. 1
Combination with ghrelin agonists
GHRH analogues and ghrelin receptor agonists such as Ipamorelin act through separate receptors. Research frequently pairs them to examine whether the combined signal exceeds either alone, which is why the blended vial exists.
References
- 1Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab (2006). PMID 16352683
Links open the record on PubMed or PubMed Central. These are citations to published research, not claims about this product.
Compare CJC-1295
Applications
Where CJC-1295 is used in the laboratory
- GHRH receptor (GHRH-R) binding and signalling studies
- Somatotroph cell culture research
- Comparative half-life and albumin-binding studies between the DAC and non-DAC forms
- Combination research alongside ghrelin receptor agonists
Verification
Does CJC-1295 come with a COA?
Yes — every box. Each batch of CJC-1295 is analysed by Janoshik Analytical or Freedom Diagnostic. The certificate confirms identity by mass spectrometry and purity by HPLC, and is tied to the batch number printed on the vial label. You can ask to see it before you order.
Example COA. You receive the certificate matching your own batch.
Questions
CJC-1295 questions, answered
What is the difference between CJC-1295 with and without DAC?
DAC stands for Drug Affinity Complex, a maleimidoproprionic acid group that binds covalently to serum albumin and substantially extends the circulating half-life. Without DAC (Modified GRF 1-29) the molecule is around 3368 g/mol and short-acting; with DAC it is around 3647 g/mol and long-acting. They are distinct compounds and are priced separately below.
How much does CJC-1295 cost?
CJC-1295 starts at $10.57 per vial, sold in boxes of 10 vials at $105.71 per box (about £83.51). 6 strengths available: 5 mg (no DAC), 10 mg (no DAC), 2 mg (with DAC), 5 mg (with DAC), 10 mg (with DAC), 5 mg + 5 mg (CJC-1295 + Ipamorelin). There is no minimum order.
What purity is your CJC-1295?
All batches test at 99%+ purity. Every box ships with a batch-specific Certificate of Analysis from Janoshik Analytical or Freedom Diagnostic, confirming identity by mass spectrometry and purity by HPLC.
Is there a minimum order for CJC-1295?
No. You can order a single box of 10 vials. There is no trade account, bulk commitment or minimum spend.
How is CJC-1295 shipped?
Tracked and in discreet, plain packaging, dispatched within 1–3 working days. Delivery estimates are UK 5–7 working days, EU 8–10, USA 5–8 and rest of world 10–12. Full detail is on the shipping page.
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